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Short Term Survival after Admission for Heart Failure in Sweden : Applying Multilevel Analyses of Discriminatory Accuracy to Evaluate Institutional Performance

机译:瑞典因心力衰竭入院后的短期生存:运用歧视性准确性的多层次分析评估机构绩效

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摘要

Background Hospital performance is frequently evaluated by analyzing differences between hospital averages in some quality indicators. The results are often expressed as quality charts of hospital variance (e.g., league tables, funnel plots). However, those analyses seldom consider patients heterogeneity around averages, which is of fundamental relevance for a correct evaluation. Therefore, we apply an innovative methodology based on measures of components of variance and discriminatory accuracy to analyze 30-day mortality after hospital discharge with a diagnosis of Heart Failure (HF) in Sweden. Methods We analyzed 36,943 patients aged 45-80 treated in 565 wards at 71 hospitals during 2007-2009. We applied single and multilevel logistic regression analyses to calculate the odds ratios and the area under the receiver-operating characteristic (AUC). We evaluated general hospital and ward effects by quantifying the intra-class correlation coefficient (ICC) and the increment in the AUC obtained by adding random effects in a multilevel regression analysis (MLRA). Finally, the Odds Ratios (ORs) for specific ward and hospital characteristics were interpreted jointly with the proportional change in variance (PCV) and the proportion of ORs in the opposite direction (POOR). Findings Overall, the average 30-day mortality was 9%. Using only patient information on age and previous hospitalizations for different diseases we obtained an AUC = 0.727. This value was almost unchanged when adding sex, country of birth as well as hospitals and wards levels. Average mortality was higher in small wards and municipal hospitals but the POOR values were 15% and 16% respectively. Conclusions Swedish wards and hospitals in general performed homogeneously well, resulting in a low 30-day mortality rate after HF. In our study, knowledge on a patient's previous hospitalizations was the best predictor of 30-day mortality, and this information did not improve by knowing the sex and country of birth of the patient or where the patient was treated.
机译:背景技术经常通过分析某些质量指标中医院平均值之间的差异来评估医院的绩效。结果通常表示为医院差异的质量图表(例如,排行榜,漏斗图)。但是,这些分析很少考虑患者在平均值附近的异质性,这对于正确评估具有根本意义。因此,我们采用了一种基于方差和区分准确度的测量方法的创新方法,来分析瑞典出院后30天的死亡率,并诊断为心力衰竭(HF)。方法我们分析了2007-2009年在71家医院的565个病房中治疗的36,943名年龄在45-80岁之间的患者。我们应用了单级和多级逻辑回归分析来计算比值比和接收者操作特征(AUC)下的面积。我们通过量化类内相关系数(ICC)和通过在多级回归分析(MLRA)中添加随机效应而获得的AUC增量来评估综合医院和病房的效应。最后,结合特定的病房和医院特征的赔率(OR)与方差的比例变化(PCV)和相反方向的OR比例(POOR)一起进行解释。调查结果总体而言,30天平均死亡率为9%。仅使用患者的年龄和以前因不同疾病住院的信息,我们得出的AUC = 0.727。当添加性别,出生国家以及医院和病房时,该值几乎没有变化。小病房和市政医院的平均死亡率较高,但POOR值分别为15%和16%。结论瑞典病房和医院总体上表现良好,HF术后30天死亡率较低。在我们的研究中,对患者先前住院治疗的知识是30天死亡率的最佳预测指标,并且该信息并不能通过了解患者的性别和出生国家或患者的治疗地点而得到改善。

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